Experimental results at RHIC and at the LHC show a similar strong suppression for light and heavy quark probes at high P-T, and a possible quark mass dependence of suppression at low P-T. More high precision measurements of separated charm and bottom are needed to quantify the dependence of medium effects on the quark mass. The PHENIX experiment measured separated electrons from bottom and charm decays using displaced vertex distributions at mid-rapidity vertical bar y vertical bar <0.35. Azimuthal anisotropy of electrons from separated charm and bottom decays are obtained from high statistics Au+Au data taken in 2014. PHENIX also measures muons from heavy quark decays in d+Au collisions at forward rapidity to study collective effects on heavy flavor production in small systems. These proceedings report the azimuthal anisotropy of charm and bottom at mid-rapidity in minimum bias Au+Au collisions and the anisotropy of single muons from heavy quark decays in d+Au collisions.